Scientific Advisors’ Publications on CFS/ME
Abstract: Cytokine, Volume 70, Issue 1, November 2014, SI: 2014 ICIS Abstract Issue
The role of cytokines in the cerebrospinal fluids of patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) Sonya Marshall-Gradisnik1, Gunnar Gottschalk2, Sandra Ramos1, Ekua Brenu1, Don Staines1, Dan Peterson2
Abstract: Clinical Translational Research Infrastructure Network June 2014
Altered Distribution of Lymphocyte Populations in Chronic Fatigue Syndrome Patients Isabel Barao, Ph.D., Daniel Peterson, M.D., Dorothy Hudig, Ph.D
BMC Research Notes 2014, 7:461 http://www.biomedcentral.com/1756-0500/7/461
No association found between the detection of either xenotropic murine leukemia virus-related virus or polytropic murine leukemia virus and chronic fatigue syndrome in a blinded, multi-site, prospective study by the establishment and use of the SolveCFS BioBank
David M Irlbeck, Suzanne D Vernon, K Kimberly McCleary, Lucinda Bateman, Nancy G Klimas, Charles W Lapp, Daniel L Peterson, James R Brown, Katja S Remlinger, David A Wilfret and Peter Gerondelis
Persistent human herpesvirus-6 infection in patients with an inherited form of the virus.
Journal of Medical Virology, 25 July 2013, doi: 10.1002/jmv.23685
Pantry, S. N., Medveczky, M. M., Arbuckle, J. H., Luka, J., Montoya, J. G., Hu, J., Renne, R., Peterson, D., Pritchett, J. C., Ablashi, D. V. and Medveczky, P. G. (2013)
Abstract: In conclusion, the data presented here document that some individuals with CIHHV-6 are infected persistently with exogenous HHV-6 strains that lead to a wide range of neurological symptoms; the proposed name for this condition is inherited herpesvirus 6 syndrome or IHS.
The adoption of chronic fatigue syndrome/myalgic encephalomyelitis case definitions to assess prevalence: a systematic review
Annals of Epidemiology Volume 23, Issue 6, Pages 371-376, June 2013
Abstract: Prevalence estimates have been based on several case definitions of chronic fatigue syndrome (CFS). The purpose of this work is to provide a rigorous overview of their application in prevalence research. Read more
Enhanced Gene Expression Following Vaccination in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
International Journal of Clinical Medicine, 2013, 4, 165-170
Abstract: The objective of this pilot study was to examine the consequences of TIV on cytokine and cytotoxic genes in CFS/ME. Read more.
Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Parallels with Autoimmune Disorders
“Genes and Autoimmunity – Intracellular Signaling and Microbiome Contribution”, book edited by Spaska Angelova Stanilova, ISBN 978-953-51-1028-6, Published: March 13, 2013
Some unexplained disorders with immune compromises may demonstrate certain characteristics that suggest an autoimmune disorder including Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). Read more here.
A Double-Blind, Placebo-Controlled, Randomized, Clinical Trial of the TLR-3 Agonist Rintatolimod in Severe Cases of Chronic Fatigue Syndrome (Ampligen)
DOI: 10.1371/journal.pone.0031334 Published: March 14, 2012
[PDF] The Effects of Influenza Vaccination on Immune Function in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
Abstract: The purpose of this pilot study was to identify the effects of influenza vaccination on immune function in patients with CFS/ME.
Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis
Journal of Translational Medicine 2012, 10:88 doi:10.1186/1479-5876-10-88 9 May 2012
Abstract: Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) is an etiologically unexplained disorder characterised by irregularities in various aspects of the immunological function. Presently, it is unknown whether these immunological changes remain consistent over time. This study investigates Natural Killer (NK) cell cytotoxic activity, NK cell subsets (CD56brightCD16- and CD56dimCD16+) and cytokines, over the course of a12 month period in patients with CFS/ME…Read more
A Multicenter Blinded Analysis Indicates No Association between Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and either Xenotropic Murine Leukemia Virus-Related Virus or Polytropic Murine Leukemia Virus
mBio 3 (5): eo266-12. doi:10.1128/mBio.oo266-12.Sept 18, 2012
Abstract: The disabling disorder known as chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) has been linked in two independent studies to infection with xenotropic murine leukemia virus-related virus (XMRV) and polytropic murine leukemia virus (pMLV). Here we report blinded analysis of peripheral blood from a rigorously characterized, geographically diverse population of 147 patients with CFS/ME and 146 healthy subjects by the investigators describing the original association. This analysis reveals no evidence of either XMRV or pMLV infection. Read more…
Cytotoxic lymphocyte microRNAs as prospective biomarkers for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
Journal of Affective Disorders 2012 May 7. 7 May 2012
Abstract: Immune dysfunction associated with a disease often has a molecular basis. A novel group of molecules known as microRNAs (miRNAs) have been associated with suppression of translational processes involved in cellular development and proliferation, protein secretion, apoptosis, immune function and inflammatory processes. MicroRNAs may be implicated in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME), where immune function is impaired. The objective of this study was to determine the association between miRNAs in cytotoxic cells and CFS/ME… Read more
Looking Forward: Dr. Peterson on ME/CFS Research, Treatment Options and Hope for the Future
22 October 2011
Dr. Dan Peterson and Dr. Cheney were the doctors on the scene as the most famous outbreak in chronic fatigue syndrome history took place in little Incline Village on the shores of Lake Tahoe high in the Sierra Nevada mountains in the early 1980’s. Both caught ‘the bug’ and both have made CFS the focus of their careers… Read more
Ekua Brenu receives Junior Investigator Research Award for CFS/ME
20 October 2011
Bond University PhD student, Ekua Brenu, was recently awarded the Junior Investigator Research Award for Chronic Fatigue Syndrome from the International Association for Chronic Fatigue Syndrome/Myalgic Encepalomyelitis (IACFS/ME) in Ottawa, Canada…. Read more