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Simmaron Scientist Awarded NIH Grant Probing Cause of Immune Holes in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

August 31, 2014

NIH Grant to Study Genetics of Immune Response in ME/CFS Simmaron Research Foundation’s Scientific Director, Isabel Barao PhD, has been awarded the IDeA Clinical and Translational Research Pilot Grant (CTR-IN) from the National Institutes of Health to examine ways ME/CFS patients’ genetic heritage may contribute to immune dysfunction and their inability to fight off viruses. […]

Simmaron Foundation’s Immunology Workshop: the Forefront of Diagnosing and Treating ME/CFS

Simmaron’s Immunology Workshop on ME/CFS, Part I Immunologists came to the Simmaron Foundation’s Immunology Workshop to decide if immune tests should be standard practice in ME/CFS diagnosis and treatment. Simmaron Research Foundation is focused on redefining ME/CFS scientifically. They produced the Immunology Workshop at the 2014 IACFS/ME Conference in order to get a consensus from […]

Simmaron Research Foundation Study Targeting Roots of Immune System Breakdown in Chronic Fatigue Syndrome (ME/CFS)

June 13, 2014

Simmaron Research’s  new immune study builds on exciting research that is changing how we think about ME/CFS. Twenty years ago  the internationally known virus hunter, Dr. Ian Lipkin of Columbia University, didn’t find Borna Virus in people with ME/CFS, but he never forgot the immune dysfunction he found.  Twenty years later he found more immune […]

Brief Report From Dr. Prigden on the Fibromyalgia Antiviral Trial – and the Future Chronic Fatigue Syndrome One

It’s not too much to say that if successful, the Pridgen antiviral trials for Fibromyalgia would be a paradigm changer – turning FM from a poorly treated central nervous system disorder to a  disorder characterized by a (hopefully) treatable herpesvirus infection. Pridgen’s approach is new in several ways. Not only has no one targeted herpesviruses […]

Could the Epstein-Barr Virus – Autoimmunity Hypothesis Help Explain Chronic Fatigue Syndrome?

( Find a ‘quick’ summary at the  bottom of the blog)   The Epstein-Barr Virus Question in ME/CFS We recently saw evidence suggesting that  increased viral loads of EBV (in whole blood) may be common in Chronic Fatigue Syndrome.We also saw that  ME/CFS patients  antibody responses to some proteins produced by EBV may be are […]

Report From San Francisco I: The “Father of Autoimmunity” Speaks

March 31, 2014

Dr. Noel Rose M.D., PhD is  the Director of the Center for Autoimmune Disorders at Johns Hopkins University. Dr. Rose has been studying autoimmunity for over sixty years  but he was a pretty darn spry 80-something at the conference. When I got close enough to  ask him a  quick question I would have sworn he […]

EBV I: A Deficient Immune Response, Increased Levels of Epstein-Barr Virus Opens Up EBV Question in Chronic Fatigue Syndrome Again

A Long History Although altered EBV-specific antibody titers have been repeatedly demonstrated in CFS, no clear evidence for chronic EBV replication has been obtained so far. Authors Perhaps the most common viral trigger for chronic fatigue syndrome (infectious mononucleosis, aka glandular fever) or Epstein Barr Virus (EBV) is a herpesvirus almost all adults have been […]

Simmaron’s Immunology Workshop at IACFS/ME: Redefining How Chronic Fatigue Syndrome Is Diagnosed and Treated

Immunology Primer For Practitioners I’ve been going to IACFS/ME conferences for eight years now and I’ve never seen a Workshop like this. This is a Workshop that could change how Chronic Fatigue Syndrome patients are tested and treated in the upcoming years. Called the “Immunology Primer for Practitioners“, it’s chaired by Dr. Daniel Peterson. It’s […]

Michael VanElzakker Ph.d Talks – About the Vagus Nerve Infection Hypothesis and Chronic Fatigue Syndrome (ME/CFS)

 An Interview with Michael VanElzakker Ph.d Michael VanElzakker’s Vagus Nerve Infection Hypothesis (VNIH) for Chronic Fatigue Syndrome may be the most intriguing hypothesis to come along in the last twenty years.  If it’s correct it could explain several mysteries including how a virus might trigger the disease and then seemingly disappear, why the Lipkin study […]

One Theory To Explain Them All? The Vagus Nerve Infection Hypothesis for Chronic Fatigue Syndrome

Big Theory It could explain the Chronic Fatigue Initiatives pathogen study results.  It could show how an infection could cause chronic fatigue syndrome, and then seemingly disappear.  It integrates two of the biggest players in ME/CFS; the autonomic nervous system and the immune system. It focuses on the herpesviruses. It includes sensory nerves, an increasingly hot […]

Big Antiviral Trial Could Usher in New Treatment Era for Fibromyalgia

 A New Approach to Fibromyalgia Infections are a common trigger for fibromyalgia (FM), and fibromyalgia patients are experience many ‘sickness behavior’ symptoms, but we haven’t usually associated FM with viruses or immune system problems. That’s been changing  recently. A immune biomarker has been proposed. Small fiber neuropathy – possibly caused by immune dysregulation – has […]

Aussie Immune Study Raises Questions About Chronic Fatigue Syndrome Research Definition

December 12, 2013

The more specific requirements of the ICC however, may select patients that are less clinically diverse. This could improve detection of immunological findings in CFS/ME.       Study authors. How much of a difference the International Consensus Criteria (or any definition) makes is a major question in chronic fatigue syndrome. Dr. Sonya Marshall-Gradisnik’s team in Australia, who […]

Dr. Peterson Reviews State of Medicine and Science of ME/CFS

Watch Dr. Peterson as he reviews the state of medicine and science of ME/CFS in a presentation to Swedish health officials:

A Talk with Dennis Mangan, New Member of Simmaron’s Scientific Advisory Board

 Communication was central to all of our activities My first memory of Dennis Mangan came at the end of a long day at a Federal Advisory Meeting for ME/CFS (CFSAC).  As the meeting broke up, Dennis strode over, pulled up a chair and motioned for everyone to gather around.  He asked what we thought needed […]

Foremost Virus Hunter Finds Biomarkers, Few Viruses in Big Chronic Fatigue Syndrome Study

A Surprise Presentation We will publish data very soon on biomarkers of cytokines. Our evidence now suggests there is ongoing stimulus to the immune system. Dr. Ian Lipkin You don’t usually get study results in talks like the one put on by  the CDC yesterday but this time Dr. Ian Lipkin spilled the beans on […]

Gunnar Gottschalk Talks About CDC Collaboration

August 20, 2013

Watch as Simmaron Research Coordinator Gunnar Gottschalk describes our collaboration in the CDC clinical assessment study. Thank you Deborah Waroff and Llewellyn King at ME/CFS Alert for continuing to follow our research progress.

Viral Finding May Open Treatment Possibilities for 15-20K Chronic Fatigue Syndrome Patients in the U.S.

More Viral Funny Business in ME/CFS Persistent human herpesvirus-6 infection in patients with an inherited form of the virus. Pantry, S, Medveczky, M, Arbuckle, J, Luka, J, Montoya, J., Hu, R. Renne, H., Peterson, D., Pritchett, J., Ablashi, D. and P. Medveczky. Journal of Medical Virology. A lot of interesting viral possibilities have been raised […]

The Simmaron ME/CFS Physicians Roundtable Pt. II: Talking Treatments

Round-Table Simmaron Research likes to get people talking. At the FDA Workshop earlier this year, they booked a room, invited patients and physicians and then held a physicians round-table with some of the field’s top doctors. Part II of a three-part series focuses on Dr. Peterson of Sierra Internal Medicine /Simmaron Research Institute, Dr. Klimas […]

ME/CFS Physicians Roundtable I: ME/CFS Docs Talk Diagnostics and More at the Simmaron Foundation Roundtable

June 18, 2013

Listen in on the field’s top experts at your own pace here! (Thanks to Anita Patton for her notes from the Roundtable talk) Simmaron likes to get people talking.  At just about every conference I’ve been to recently, the Simmaron Foundation has rented a room, brought in some food and got patients, doctors and researchers […]

Recordings from Simmaron’s Roundtable: Scientifically Redefining ME/CFS

Simmaron’s Pre-FDA Workshop Roundtable: Scientifically Redefining ME/CFS, April 25, 2013 Simmaron Scientific Advisor Dr. Daniel Peterson hosted a roundtable discussion in the hours before the FDA’s Drug Development Workshop. He is joined by Dr. Nancy Klimas, Dr. Derek Enlander, Dr. Charles Lapp and Simmaron Researcher Gunnar Gottschalk to discuss state of the art diagnosis and clinical […]

Novel Approach to Herpesvirus Infections Could Reap Dividends for Chronic Fatigue Syndrome Patients

Liang Y, Vogel JL, Arbuckle JH, Rai G, Jadhav A, Simeonov A, Maloney DJ, Kristie TM. Targeting the JMJD2 Histone Demethylases to Epigenetically Control Herpesvirus Infection and Reactivation from Latency. Sci Transl Med. 2013 Jan 9. PMID: 23303604. Common Infections..Sometimes Uncommon Effects Herpesviruses are fundamentally different from most other viruses we come into contact with. […]

Patient Bob Miller Skydives to Raise Funds for Simmaron!

Taking Fundraising for ME/CFS Research to New Heights! ME/CFS Patient Robert Miller and Research Coordinator Gunnar Gottschalk PARACHUTE from 13,000 feet to raise funds for Simmaron Research!  Simmaron has 2 new studies to help Scientifically Redefine ME/CFS, so Bob and Gunnar took to the skies on ME/CFS Awareness Day to inspire patients to invest in […]

Gunnar Gottschalk SkyDives to Raise Funds for Simmaron!

Taking Fundraising for ME/CFS Research to New Heights! ME/CFS Patient Robert Miller and Research Coordinator Gunnar Gottschalk PARACHUTE from 13,000 feet to raise funds for Simmaron Research!  Simmaron has 2 new studies to help Scientifically Redefine ME/CFS, so Bob and Gunnar took to the skies to inspire patients to invest in our science. Watch them […]

Dr. Peterson Calls for “Therapeutic Strategy” to Develop Drugs for ME/CFS

“We’re Ready” Dr. Peterson had 2 minutes to get to the point. And he did. After 30 years of treating approximately 9,000 patients and tired of the ‘therapeutic stagnation’ in this disease, he called on the FDA to ‘execute a therapeutic strategy’ that would pave the way for drug development. No doubt speaking not just […]

FDA Drug Development Workshop Real Time Tweets

Below are Simmaron Research’s real time tweets from the FDA Drug Development Workshop on April 25th and April 26th last week. They are notes from most of the workshop sessions. While tweets usually have the most recent on top we have swapped this so the tweets here are in chronological order so you can follow […]

Your Brain on Viruses: Study Finds Even Common Viruses Cause Cognitive Declines

The ‘Manhattan Project’ The Northern Manhattan Study is an immense project that’s taking a deep look at health in Northern Manhattan, New York . The project consists of  analyzing basic health characteristics of several  thousand people over time and it’s spinning out studies at a dizzying rate.  The project is not on chronic fatigue syndrome, […]

Report From Paris: Peterson Reports Antiviral (Vistide) Effective in Treating Herpesvirus Infected Chronic Fatigue Syndrome (ME/CFS) Patients

“These results show objective endpoints, subset selection, and recovery. There were complete responders and partial responders among severely ill CFS patients with HHV6 or CMV. These are encouraging results for this subset and further well-designed trials should be pursued to confirm them.” Dr. Dan Peterson At the HHV6 Conference in Paris, France today Dr. Peterson reported […]

Simmaron Research Mobilizes Unique Assets to Push ME/CFS Field Forward: A Look Back at the First Year

April 4, 2013

We envision a world where ME/CFS is treatable and well-understood. To get there, we are scientifically redefining ME/CFS. The latest addition to the ME/CFS Research Foundation scene, the Simmaron Research Foundation started off small. There were no huge endowments, no connections to major academic centers; in fact, Simmaron was located in little Incline Village off […]

Infection, Autoimmunity and PANDA’s: Dr. Hornig on Chronic Fatigue Syndrome at Dr. Klimas’ NSU Conference

Quite the Resume Dr Mady Hornig comes with quite a resume. She and Dr. Ian Lipkin MD direct the Center for Infection and Immunity at Columbia University in New York, and Dr. Hornig is directing the Pathogen Discovery and Pathogenesis Program at the Chronic Fatigue Initiative (CFI). An MD and immunologist with a background in […]

Great Start – Big Plans Ahead: Dr. Klimas at her NSU Coming Out Party

A Coming Out Party The coming out party for Dr. Klimas Institute for Neuroimmune Research at Nova Southeastern University (NSU) on January 26th was a year in the making.   In 2011 NSU had made her an offer she couldn’t refuse -  the opportunity to break down what she called the  silo’s that separated researchers, clinicians […]

FDA Advisory Meeting on Ampligen and Chronic Fatigue Syndrome (ME/CFS) Pt I: Dueling Presentations Set the Stage For Critical Vote

The Great Room We were in the ‘Great room’ and it was  a great room; an impressive  room able to seat several hundred people with large screens covering the sides of one wall so that everybody had a clear view of what was going on.  With the FDA often following FDA Advisory Committee recommendations this […]

Harsh FDA Report…Good Committee…Which Way Ampligen?

December 20, 2012

The meeting webcast can be accessed at the following web address:   https://collaboration.fda.gov/aac122012/  At the access page  sign in as a guest. No password is required. For more info click here. Agenda 8:00 AM EST: Meeting Opens 8:20-9:50 – Hemispherx Presents 10:20-12:00 – FDA Presents 1-2:30 Public Presents 3-5:00 – The Committee answers the FDA’s questions and then […]

Dec 20th: High Noon for Ampligen and Chronic Fatigue Syndrome

December 16, 2012

by Cort Johnson Ampligen’s time is finally here.  Twenty years of effort and hope  will culminate on the early evening of Dec 20th, when, following an  all-day hearing,  an FDA Advisory committee  will determine  Ampligen’s fate. Palms will be sweating and hearts will be pounding that evening as patients, physicians and their supporters and researchers […]

Interview with Dr. Daniel Peterson, Scientific Advisor

Interview with Dr. Daniel Peterson, Scientific Advisor Video by Llewellyn King of ME/CFS Alert

Courtney Miller Asks President Obama for Help